Publications

Fowler, A.L., Shah, K., Panepinto, J.C., Jacobs, A., Koffas, M.A.G. Antimicrobial drug discovery through chemical synthesis of non-natural flavanones. PLOS One [In Press] (2011).

Yi, H.Y., Panepinto, J.C., Jacobs, A. Inhibition of HIV entry by extracellular glucuronoxylomannan of Cryptococcus neoformans. Microbial Pathogenesis. Oct. 2 [Epub ahead of print] (2011).

Yi, H.A., Diaz-Aguilar, B., Bridon, D., Quraishi, O.,Jacobs, A. Permanent Inhibition of Viral Entry by Covalent Entrapment of HIV gp41 on the Virus Surface. Biochemistry. Aug 16; 50 (32): 6966-72 (2011).

Huang, K., Jacobs, A., Rzayev, J. De Novo Synthesis and Cellular Uptake of Organic Nanocapsules with Tunable Surface Chemistry. Biomacromolecule.  Jun 13; 12(6): 2327-34 (2011).

Garg, H., Viard, M., Jacobs, A., Blumenthal, R. Lipophlic and Amphiphilic Interactions in Glycoprotein 41: Targets for Therapy; Current Topics in Medicinal Chemistry. [In press] (2011).

Zielinski, R., Lyakhov, I., Jacobs, A., Chertov, O., Kramer-Marek, G., Francella, N., Stephen, A., Fisher, R., Blumenthal, R., Capala, J. Affitoxin-A Novel Recombinant, HER2-Specific, Anti-Cancer Agent for Targeted Therapy of HER2-Positive Tumors. Journal of Immunotherapy. Oct; 32(8):817-25 (2009).

Jacobs, A., Blumenthal, R. Understanding the Design Principles of Living Systems at the Nanoscale. Current Nanoscience 5 (1): 45-50(6) (2009).

Jacobs, A, Garg, H., Viard, M., Raviv, Y., Puri, A., Blumenthal, R. HIV-1 Envelope Glycoprotein-Mediated Fusion and Pathogenesis: Implications for Therapy and Vaccine Development. Vaccine. 26 (24): 3026-35 (2008)

Jacobs, A., Quraishi, O., Francella, N., Bridon, D., Blumenthal, R. A covalent inhibitor targeting an intermediate conformation of the fusogenic subunit of the HIV-1 envelope complex. J. Biol. Chem. 282 (44): 32406-13 (2007).

Sen, J., Jacobs, A., Jiang, H., Rong, L., Caffrey, M. The disulfide loop of gp41 is critical to the furin recognition site of HIV gp160. Protein Sci. 16 (6):1236-41 (2007).

Jacobs, A., Dimitrov, A.S., Finnegan, C.M.,Stiegler, G.,Katinger, H., Blumenthal, R. Exposure of the membrane-proximal external region of HIV-1 envelope glycoprotein-mediated fusion. Biochemistry. 280 (29):27284-8 (2005).

Jacobs, A., Simon, C., Caffrey, M. Thermostability of the HIV gp41 wild-type and loop mutations. Protein Pept. Lett. 13 (5): 477-80 (2006).

Jacobs A., Caffrey M. Alanine scanning mutants of the HIV gp41 loop. J. Biol. Chem. May 24 (2005).

Jacobs A., Hartman K, Laue T, Caffrey, M. Sedimentation velocity studies of the high-molecular weight aggregates of the HIV gp41 ectodomain. Protein Science. 13 (10): 2811-3 (2004).

Jiang S., Jacobs A., Laue T., Caffrey M. Solution structure of the coxsackievirus and adenovirus receptor domain 1. Biochemistry. 43 (7): 1847-53 (2004).

Gilhaudis L., Jacobs A., Caffrey M. Solution Structure of the HIV gp120 C5 Domain. Eur. J. Biochem. 269 (19): 4860-7 (2002).

Hakansson S., Jacobs A., Caffrey M. Heparin binding by the HIV-1 tat protein transduction domain. Protein Science. 10 (10): 2138-9 (2001).